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NPR's Ailsa Chang speaks with David Schweikert, an Arizona congressman and Freedom Caucus member, about House spending bill negotiations as the possibility of a partial government shutdown looms.

NPR's Mary Louise Kelly talks with Daniel Byman, senior fellow in the Center for Middle East Policy at the Brookings Institution, about the status of ISIS operations in Syria.

The retired Marine general had been granted a rare waiver to run the Pentagon as he had been out of uniform for only three years, but his relationship with President Trump eventually turned cold.

In an interview with NPR, Secretary of State Mike Pompeo expanded on remarks by President Trump, who declared the U.S. had "won against ISIS" and would pull troops from Syria.

The $12.8 billion deal gives the parent company of Philip Morris a way to hedge its bets as U.S. cigarette smoking declines. And it gives Juul a powerful partner as it faces scrutiny over teen vaping.

President Trump's Defense Secretary has resigned. NPR's Mary Louise Kelly speaks with New Yorker staff writer Dexter Filkins.

The announcement that Secretary of Defense Jim Mattis will retire comes during a tumultuous week for the White House.

NPR's Mary Louise Kelly speaks to retired General Jack Keane, who had personally recommended General Mattis to Trump. He comments on General Mattis's resignation today as Secretary of Defense.

Research suggests the winter blues are triggered by specialized light-sensing cells in the retina that communicate directly with brain areas involved in mood.

It's the holiday edition of everyone's favorite trope! A new NPR/PBS NewsHour/Marist Poll tracks cultural changes in shopping and celebrating. But why not keep attributing them to generational whims?