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New evidence suggests the first recorded game of baseball took place in Surrey in 1749. Guest host Linda Wertheimer has the details.

Despite enormous progress over the last century, cardiovascular disease is the most common cause of death in the United States and other developed nations. Guest host Linda Wertheimer and Cleveland Clinic Cardiology Chairman Dr. Steven Nissen talk about why so many Americans continue to die of heart disease, even though it's largely treatable.

Trial observers wait to see whether notorious mobster Whitey Bulger will take the stand in his own defense. Guest host Linda Wertheimer talks to reporter David Boeri of member station WBUR in Boston, whose been covering the trial.

The comedienne's routines tackle some of the really serious problems she has. Transcripts of filmmaker Henry Jaglom's conversations with Orson Welles have been released in a new book. David Gilbert tells the story of an aging writer whose children do not feel as warmly toward him as his readers do.

In 1973, she succeeded her husband in a special election and served for nearly two decades. She later became ambassador to the Vatican under President Bill Clinton.

Jenni Fagan's debut novel, The Panopticon, is a creepy and troubled portrait of a girl lost in the system. The plot is loosely based on Fagan's experience growing up in foster care.

The drug war was in full swing in the '80s, and cocaine was practically everywhere. But use of the drug has fallen by almost half since 2006, and production is also down significantly. How did the U.S. kick the habit? Experts say cocaine has lost its luster — oh and policy may have made a difference, too.

Supporters of ousted President Mohammed Morsi clashed with authorities in one of the country's deadliest days in years. Though each side tells a different version of what caused the violence, analysts say it signals a change in how the military will handle the Muslim Brotherhood.

Throughout Detroit's long decline, city planners and ordinary people have launched countless plans to revive the city — casinos, downtown development, urban farms, artist hubs. One city neighborhood is thinking small, and it's starting to pay off big.

Some American yachts in the prestigious sailing race are so advanced, few can compete. Weekend Edition Sunday guest host Susan Stamberg talks with NPR's Mike Pesca about boat races, and about a little bit of football math.